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Excess Secretion of Gel-Forming Mucins and Associated Innate Defense Proteins with Defective Mucin Un-Packaging Underpin Gallbladder Mucocele Formation in Dogs
Mucosal protection of the gallbladder is vital yet we know very little about the mechanisms involved. In domestic dogs, an emergent syndrome referred to as gallbladder mucocele formation is characterized by excessive secretion of abnormal mucus that results in obstruction and rupture of the gallblad...
Autores principales: | Kesimer, Mehmet, Cullen, John, Cao, Rui, Radicioni, Giorgia, Mathews, Kyle G., Seiler, Gabriela, Gookin, Jody L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586375/ https://www.ncbi.nlm.nih.gov/pubmed/26414376 http://dx.doi.org/10.1371/journal.pone.0138988 |
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