Cargando…

Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1

Hepatic stellate cell (HSC) activation and trans-differentiation into myofibroblast (MFB)-like cells is key for fibrogenesis after liver injury and a potential therapeutic target. Recent studies demonstrated that low-density lipoprotein receptor-related protein 1 (LRP1)-dependent signaling by tissue...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Liang-I, Isse, Kumiko, Koral, Kelly, Bowen, William C, Muratoglu, Selen, Strickland, Dudley K, Michalopoulos, George K, Mars, Wendy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586397/
https://www.ncbi.nlm.nih.gov/pubmed/26237273
http://dx.doi.org/10.1038/labinvest.2015.94