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Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1
Hepatic stellate cell (HSC) activation and trans-differentiation into myofibroblast (MFB)-like cells is key for fibrogenesis after liver injury and a potential therapeutic target. Recent studies demonstrated that low-density lipoprotein receptor-related protein 1 (LRP1)-dependent signaling by tissue...
Autores principales: | Kang, Liang-I, Isse, Kumiko, Koral, Kelly, Bowen, William C, Muratoglu, Selen, Strickland, Dudley K, Michalopoulos, George K, Mars, Wendy M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586397/ https://www.ncbi.nlm.nih.gov/pubmed/26237273 http://dx.doi.org/10.1038/labinvest.2015.94 |
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