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Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor Immunity

Transcription is a dynamic process influenced by the cellular environment: healthy, transformed, and otherwise. Genome-wide mRNA expression profiles reflect the collective impact of pathways modulating cell function under different conditions. In this review we focus on the transcriptional pathways...

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Detalles Bibliográficos
Autores principales: Waugh, Katherine A., Leach, Sonia M., Slansky, Jill E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586477/
https://www.ncbi.nlm.nih.gov/pubmed/26393659
http://dx.doi.org/10.3390/vaccines3030771