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PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells

Splicing factors are key players in the regulation of alternative splicing of pre-mRNAs. Overexpression of splicing factors, including SRSF3, has been strongly linked with oncogenesis. However, the mechanisms behind their overexpression remain largely unclear. Autoregulation is a common mechanism to...

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Detalles Bibliográficos
Autores principales: Guo, Jihua, Jia, Jun, Jia, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586487/
https://www.ncbi.nlm.nih.gov/pubmed/26416554
http://dx.doi.org/10.1038/srep14548