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Melanin production through novel processing of proopiomelanocortin in the extracellular compartment of the auricular skin of C57BL/6 mice after UV-irradiation

The production of melanin is regulated by α-melanocyte-stimulating hormone (α-MSH), which is produced from proopiomelanocortin (POMC). Keratinocytes release POMC along with lower levels of α-MSH and ACTH. To clarify the mechanism of melanogenesis after ultraviolet (UV)-irradiation, this study focuse...

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Detalles Bibliográficos
Autores principales: Yamamoto, Hiroyuki, Yamane, Tomohiro, Iguchi, Kazuaki, Tanaka, Kiyotaka, Iddamalgoda, Arunasiri, Unno, Keiko, Hoshino, Minoru, Takeda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586518/
https://www.ncbi.nlm.nih.gov/pubmed/26417724
http://dx.doi.org/10.1038/srep14579