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Melanin production through novel processing of proopiomelanocortin in the extracellular compartment of the auricular skin of C57BL/6 mice after UV-irradiation

The production of melanin is regulated by α-melanocyte-stimulating hormone (α-MSH), which is produced from proopiomelanocortin (POMC). Keratinocytes release POMC along with lower levels of α-MSH and ACTH. To clarify the mechanism of melanogenesis after ultraviolet (UV)-irradiation, this study focuse...

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Detalles Bibliográficos
Autores principales:	Yamamoto, Hiroyuki, Yamane, Tomohiro, Iguchi, Kazuaki, Tanaka, Kiyotaka, Iddamalgoda, Arunasiri, Unno, Keiko, Hoshino, Minoru, Takeda, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586518/ https://www.ncbi.nlm.nih.gov/pubmed/26417724 http://dx.doi.org/10.1038/srep14579

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