Reconciling depressed Ca(2+) sparks occurrence with enhanced RyR2 activity in failing mice cardiomyocytes

Abnormalities in cardiomyocyte Ca(2+) handling contribute to impaired contractile function in heart failure (HF). Experiments on single ryanodine receptors (RyRs) incorporated into lipid bilayers have indicated that RyRs from failing hearts are more active than those from healthy hearts. Here, we an...

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Detalles Bibliográficos
Autores principales: Ruiz-Hurtado, Gema, Li, Linwei, Fernández-Velasco, María, Rueda, Angélica, Lefebvre, Florence, Wang, Yueyi, Mateo, Philippe, Cassan, Cécile, Gellen, Barnabas, Benitah, Jean Pierre, Gómez, Ana María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586588/
https://www.ncbi.nlm.nih.gov/pubmed/26371209
http://dx.doi.org/10.1085/jgp.201511366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586588/
https://www.ncbi.nlm.nih.gov/pubmed/26371209
http://dx.doi.org/10.1085/jgp.201511366

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