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Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin

Signal transduction via integrins and G protein–coupled receptors is critical to control cell behavior. These two receptor classes have been traditionally believed to trigger distinct and independent signaling cascades in response to extracellular cues. Here, we report a novel mechanism of integrin...

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Detalles Bibliográficos
Autores principales: Leyme, Anthony, Marivin, Arthur, Perez-Gutierrez, Lorena, Nguyen, Lien T., Garcia-Marcos, Mikel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586755/
https://www.ncbi.nlm.nih.gov/pubmed/26391662
http://dx.doi.org/10.1083/jcb.201506041