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Claudin11 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin, but Uncommon in Nevus Cell Nevi

Epigenetic inactivation of tumor-related genes is an important characteristic in the pathology of human cancers, including melanomagenesis. We analyzed the epigenetic inactivation of Claudin 11 (CLDN11) in malignant melanoma (MM) of the skin, including six melanoma cell lines, 39 primary melanoma, 4...

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Detalles Bibliográficos
Autores principales: Walesch, Sara K., Richter, Antje M., Helmbold, Peter, Dammann, Reinhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586767/
https://www.ncbi.nlm.nih.gov/pubmed/26198249
http://dx.doi.org/10.3390/cancers7030834