Not so Fast: Co-Requirements for Sonic Hedgehog Induced Brain Tumorigenesis

The Sonic hedgehog (Shh) pathway plays an integral role in cellular proliferation during normal brain development and also drives growth in a variety of cancers including brain cancer. Clinical trials of Shh pathway inhibitors for brain tumors have yielded disappointing results, indicating a more nu...

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Detalles Bibliográficos
Autores principales: Ward, Stacey A., Rubin, Joshua B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586781/
https://www.ncbi.nlm.nih.gov/pubmed/26258793
http://dx.doi.org/10.3390/cancers7030848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586781/
https://www.ncbi.nlm.nih.gov/pubmed/26258793
http://dx.doi.org/10.3390/cancers7030848

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