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Acute Traumatic Brain Injury Does Not Exacerbate Amyotrophic Lateral Sclerosis in the SOD1(G93A) Rat Model1,2,3

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease in which upper and lower motor neurons degenerate, leading to muscle atrophy, paralysis, and death within 3 to 5 years of onset. While a small percentage of ALS cases are genetically linked, the majority are sporadic with unknown or...

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Detalles Bibliográficos
Autores principales: Thomsen, Gretchen M., Vit, Jean-Philippe, Lamb, Alexander, Gowing, Genevieve, Shelest, Oksana, Alkaslasi, Mor, Ley, Eric J., Svendsen, Clive N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586929/
https://www.ncbi.nlm.nih.gov/pubmed/26464984
http://dx.doi.org/10.1523/ENEURO.0059-14.2015