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Extracellular environment contribution to astrogliosis—lessons learned from a tissue engineered 3D model of the glial scar

Glial scars are widely seen as a (bio)mechanical barrier to central nervous system regeneration. Due to the lack of a screening platform, which could allow in-vitro testing of several variables simultaneously, up to now no comprehensive study has addressed and clarified how different lesion microenv...

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Detalles Bibliográficos
Autores principales: Rocha, Daniela N., Ferraz-Nogueira, José P., Barrias, Cristina C., Relvas, João B., Pêgo, Ana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586948/
https://www.ncbi.nlm.nih.gov/pubmed/26483632
http://dx.doi.org/10.3389/fncel.2015.00377