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Extracellular environment contribution to astrogliosis—lessons learned from a tissue engineered 3D model of the glial scar
Glial scars are widely seen as a (bio)mechanical barrier to central nervous system regeneration. Due to the lack of a screening platform, which could allow in-vitro testing of several variables simultaneously, up to now no comprehensive study has addressed and clarified how different lesion microenv...
Autores principales: | Rocha, Daniela N., Ferraz-Nogueira, José P., Barrias, Cristina C., Relvas, João B., Pêgo, Ana P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586948/ https://www.ncbi.nlm.nih.gov/pubmed/26483632 http://dx.doi.org/10.3389/fncel.2015.00377 |
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