Identification of Bexarotene as a PPARγ Antagonist with HDX

The retinoid x receptors (RXRs) are the pharmacological target of Bexarotene, an antineoplastic agent indicated for the treatment of cutaneous T cell lymphoma (CTCL). The RXRs form heterodimers with several nuclear receptors (NRs), including peroxisome proliferator-activated receptor gamma (PPARγ),...

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Detalles Bibliográficos
Autores principales: Marciano, David P., Kuruvilla, Dana S., Pascal, Bruce D., Griffin, Patrick R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586960/
https://www.ncbi.nlm.nih.gov/pubmed/26451138
http://dx.doi.org/10.1155/2015/254560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586960/
https://www.ncbi.nlm.nih.gov/pubmed/26451138
http://dx.doi.org/10.1155/2015/254560

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