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Identification of Bexarotene as a PPARγ Antagonist with HDX

The retinoid x receptors (RXRs) are the pharmacological target of Bexarotene, an antineoplastic agent indicated for the treatment of cutaneous T cell lymphoma (CTCL). The RXRs form heterodimers with several nuclear receptors (NRs), including peroxisome proliferator-activated receptor gamma (PPARγ),...

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Detalles Bibliográficos
Autores principales:	Marciano, David P., Kuruvilla, Dana S., Pascal, Bruce D., Griffin, Patrick R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586960/ https://www.ncbi.nlm.nih.gov/pubmed/26451138 http://dx.doi.org/10.1155/2015/254560

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