Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase

Matrix metalloproteinases (MMPs) have been designated as both friend and foe in the central nervous system (CNS): while being involved in many neurodegenerative and neuroinflammatory diseases, their actions appear to be indispensable to a healthy CNS. Pathological conditions in the CNS are therefore...

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Detalles Bibliográficos
Autores principales: De Groef, Lies, Salinas-Navarro, Manuel, Van Imschoot, Griet, Libert, Claude, Vandenbroucke, Roosmarijn E., Moons, Lieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586990/
https://www.ncbi.nlm.nih.gov/pubmed/26451076
http://dx.doi.org/10.1155/2015/108617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586990/
https://www.ncbi.nlm.nih.gov/pubmed/26451076
http://dx.doi.org/10.1155/2015/108617

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