Cargando…

Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase

Matrix metalloproteinases (MMPs) have been designated as both friend and foe in the central nervous system (CNS): while being involved in many neurodegenerative and neuroinflammatory diseases, their actions appear to be indispensable to a healthy CNS. Pathological conditions in the CNS are therefore...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Groef, Lies, Salinas-Navarro, Manuel, Van Imschoot, Griet, Libert, Claude, Vandenbroucke, Roosmarijn E., Moons, Lieve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586990/ https://www.ncbi.nlm.nih.gov/pubmed/26451076 http://dx.doi.org/10.1155/2015/108617

Ejemplares similares

MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment
por: Van Hove, Inge, et al.
Publicado: (2016)

The first MMP in sepsis
por: Vandenbroucke, Roosmarijn E, et al.
Publicado: (2011)

MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System
por: Andries, Lien, et al.
Publicado: (2021)

Matrix metalloproteinases in the mouse retina: a comparative study of expression patterns and MMP antibodies
por: De Groef, Lies, et al.
Publicado: (2015)

A New Venue of TNF Targeting
por: Steeland, Sophie, et al.
Publicado: (2018)

Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice
por: De Groef, Lies, et al.
Publicado: (2016)

Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease
por: Steeland, Sophie, et al.
Publicado: (2018)

Target-Derived Neurotrophic Factor Deprivation Puts Retinal Ganglion Cells on Death Row: Cold Hard Evidence and Caveats
por: Claes, Marie, et al.
Publicado: (2019)

Molecular Mechanisms of Neural Circuit Development and Regeneration
por: Moons, Lieve, et al.
Publicado: (2021)

Effect of telmisartan on levels of IL-1, TNF-α, down-regulated COX-2, MMP-2, MMP-9 and RANKL/RANK in an experimental periodontitis model
por: Araújo, Aurigena A, et al.
Publicado: (2013)

Expression of MMP-2 and MMP-9 in the rat trigeminal ganglion during the development of temporomandibular joint inflammation
por: Nascimento, G.C., et al.
Publicado: (2013)

Characterizing microglia activation: a spatial statistics approach to maximize information extraction
por: Davis, Benjamin M., et al.
Publicado: (2017)

Complementary research in mammals and fish indicates MMP-2 as a pleiotropic contributor to optic nerve regeneration
por: Lemmens, Kim, et al.
Publicado: (2016)

A novel retinal ganglion cell quantification tool based on deep learning
por: Masin, Luca, et al.
Publicado: (2021)

Mice Overexpressing β-1,4-Galactosyltransferase I Are Resistant to TNF-Induced Inflammation and DSS-Induced Colitis
por: Vanhooren, Valerie, et al.
Publicado: (2013)

Inhibition of MMP1, MMP2 and MMP8 by mepacrine
por: Pollaschek, C, et al.
Publicado: (2003)

The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox
por: Claes, Marie, et al.
Publicado: (2022)

Mycobacterium tuberculosis Upregulates TNF-α Expression via TLR2/ERK Signaling and Induces MMP-1 and MMP-9 Production in Human Pleural Mesothelial Cells
por: Chen, Wei-Lin, et al.
Publicado: (2015)

Carvedilol Decrease IL-1β and TNF-α, Inhibits MMP-2, MMP-9, COX-2, and RANKL Expression, and Up-Regulates OPG in a Rat Model of Periodontitis
por: de Araújo Júnior, Raimundo Fernandes, et al.
Publicado: (2013)

Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas
por: Meneses-García, Abelardo, et al.
Publicado: (2008)

TNF-α-Induced VEGF and MMP-9 Expression Promotes Hemorrhagic Transformation in Pituitary Adenomas
por: Xiao, Zhengzheng, et al.
Publicado: (2011)

166 Assessment of Chronic Spontaneous Urticaria by Serum-Induced TNF & ALPHA; and MMP-9 Release
por: Falkencronec, Sidsel, et al.
Publicado: (2012)

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF
por: Vandenbroucke, Roosmarijn E, et al.
Publicado: (2013)

MMP-2 and sTNF-R1 Variability in Patients with Essential Hypertension: 1-Year Follow-Up Study
por: Carpena, Núria, et al.
Publicado: (2012)

The Effect of Two Types of Exercise Preconditioning on the Expression of TrkB, TNF-α, and MMP2 Genes in Rats with Stroke
por: Teymuri Kheravi, Mostafa, et al.
Publicado: (2021)

TIMP-3 suppresses the proliferation and migration of SMCs from the aortic neck of atherosclerotic AAA in rabbits, via decreased MMP-2 and MMP-9 activity, and reduced TNF-α expression
por: Zhai, Huan, et al.
Publicado: (2018)

Olmesartan Decreased Levels of IL-1β and TNF-α, Down-Regulated MMP-2, MMP-9, COX-2, RANK/RANKL and Up-Regulated SOCs-1 in an Intestinal Mucositis Model
por: de Araújo Júnior, Raimundo Fernandes, et al.
Publicado: (2014)

Helicobacter pylori‐derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3‐C3aR signalling
por: Xie, Junhua, et al.
Publicado: (2023)

Regulation of monocyte MMP-9 production by TNF-alpha and a tumour-derived soluble factor (MMPSF).
por: Leber, T. M., et al.
Publicado: (1998)

Prognostic Markers for Chorioamnionitis: IL-6, TNF-α, and MMP-8 in Vaginally Obtained Amniotic Fluid
por: Balciuniene, Greta, et al.
Publicado: (2021)

Toward Point-of-Care Diagnostics to Monitor MMP-9 and TNF-α Levels in Inflammatory Bowel Disease
por: Liu, Dandan, et al.
Publicado: (2021)

MMP2 and MMP9 associate with crescentic glomerulonephritis
por: Phillips, Tessa M., et al.
Publicado: (2017)

TNFR1 inhibition with a Nanobody protects against EAE development in mice
por: Steeland, Sophie, et al.
Publicado: (2017)

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1
por: Puimège, Leen, et al.
Publicado: (2015)

Correction: Olmesartan Decreased Levels of IL-1β and TNF-α, Down-Regulated MMP-2, MMP-9, COX-2, RANK/RANKL and Up-Regulated SOCs-1 in an Intestinal Mucositis Model
Publicado: (2015)

Immunohistochemical expression of MMP-14 and MMP-2, and MMP-2 activity during human ovarian follicular development
por: Vos, Maria Caroline, et al.
Publicado: (2014)

Assessment of the concentration of selected metalloproteinases (MMP-2, MMP-3, MMP-9 and MMP-13) in patients with ulcers as a complication of type 2 diabetes
por: Kupczyk, Daria, et al.
Publicado: (2020)

Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma
por: Nosratzehi, Tahereh, et al.
Publicado: (2017)

Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (MMP1, MMP2, MMP3, and MMP9) Genes with Preeclampsia
por: Sakowicz, Agata, et al.
Publicado: (2018)

Effects of Er-Miao-San extracts on TNF-alpha-induced MMP-1 expression in human dermal fibroblasts
por: Bae, Seunghee, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_r4jj7l62ns2v823q2gpqr11e71