Drug-Free Platelets Can Act as Seeds for Aggregate Formation During Antiplatelet Therapy

OBJECTIVE—: Reduced antiplatelet drug efficacy occurs in conditions of increased platelet turnover, associated with increased proportions of drug-free, that is, uninhibited, platelets. Here, we detail mechanisms by which drug-free platelets promote platelet aggregation in the face of standard antipl...

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Detalles Bibliográficos
Autores principales: Hoefer, Thomas, Armstrong, Paul C., Finsterbusch, Michaela, Chan, Melissa V., Kirkby, Nicholas S., Warner, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587545/
https://www.ncbi.nlm.nih.gov/pubmed/26272940
http://dx.doi.org/10.1161/ATVBAHA.115.306219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587545/
https://www.ncbi.nlm.nih.gov/pubmed/26272940
http://dx.doi.org/10.1161/ATVBAHA.115.306219

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