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Drug-Free Platelets Can Act as Seeds for Aggregate Formation During Antiplatelet Therapy
OBJECTIVE—: Reduced antiplatelet drug efficacy occurs in conditions of increased platelet turnover, associated with increased proportions of drug-free, that is, uninhibited, platelets. Here, we detail mechanisms by which drug-free platelets promote platelet aggregation in the face of standard antipl...
Autores principales: | Hoefer, Thomas, Armstrong, Paul C., Finsterbusch, Michaela, Chan, Melissa V., Kirkby, Nicholas S., Warner, Timothy D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587545/ https://www.ncbi.nlm.nih.gov/pubmed/26272940 http://dx.doi.org/10.1161/ATVBAHA.115.306219 |
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