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Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke

The use and effectiveness of current stroke reperfusion therapies are limited by the complications of reperfusion injury, which include increased cerebrovascular permeability and haemorrhagic transformation. Sphingosine-1-phosphate (S1P) is emerging as a potent modulator of vascular integrity via it...

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Detalles Bibliográficos
Autores principales: Kim, Gab Seok, Yang, Li, Zhang, Guoqi, Zhao, Honggang, Selim, Magdy, McCullough, Louise D., Kluk, Michael J., Sanchez, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587559/
https://www.ncbi.nlm.nih.gov/pubmed/26243335
http://dx.doi.org/10.1038/ncomms8893