Plaque2.0—A High-Throughput Analysis Framework to Score Virus-Cell Transmission and Clonal Cell Expansion

Classical plaque assay measures the propagation of infectious agents across a monolayer of cells. It is dependent on cell lysis, and limited by user-specific settings and low throughput. Here, we developed Plaque2.0, a broadly applicable, fluorescence microscopy-based high-throughput method to mine...

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Detalles Bibliográficos
Autores principales: Yakimovich, Artur, Andriasyan, Vardan, Witte, Robert, Wang, I-Hsuan, Prasad, Vibhu, Suomalainen, Maarit, Greber, Urs F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587671/
https://www.ncbi.nlm.nih.gov/pubmed/26413745
http://dx.doi.org/10.1371/journal.pone.0138760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587671/
https://www.ncbi.nlm.nih.gov/pubmed/26413745
http://dx.doi.org/10.1371/journal.pone.0138760

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