Cargando…

Plaque2.0—A High-Throughput Analysis Framework to Score Virus-Cell Transmission and Clonal Cell Expansion

Classical plaque assay measures the propagation of infectious agents across a monolayer of cells. It is dependent on cell lysis, and limited by user-specific settings and low throughput. Here, we developed Plaque2.0, a broadly applicable, fluorescence microscopy-based high-throughput method to mine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yakimovich, Artur, Andriasyan, Vardan, Witte, Robert, Wang, I-Hsuan, Prasad, Vibhu, Suomalainen, Maarit, Greber, Urs F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587671/ https://www.ncbi.nlm.nih.gov/pubmed/26413745 http://dx.doi.org/10.1371/journal.pone.0138760

Ejemplares similares

Label-Free Digital Holo-tomographic Microscopy Reveals Virus-Induced Cytopathic Effects in Live Cells
por: Yakimovich, Artur, et al.
Publicado: (2018)

Concepts in Light Microscopy of Viruses
por: Witte, Robert, et al.
Publicado: (2018)

Microscopy deep learning predicts virus infections and reveals mechanics of lytic-infected cells
por: Andriasyan, Vardan, et al.
Publicado: (2021)

A high-content image-based drug screen of clinical compounds against cell transmission of adenovirus
por: Georgi, Fanny, et al.
Publicado: (2020)

The FDA-Approved Drug Nelfinavir Inhibits Lytic Cell-Free but Not Cell-Associated Nonlytic Transmission of Human Adenovirus
por: Georgi, Fanny, et al.
Publicado: (2020)

Virus Infection Variability by Single-Cell Profiling
por: Suomalainen, Maarit, et al.
Publicado: (2021)

Label-free microscopy for virus infections
por: Petkidis, Anthony, et al.
Publicado: (2023)

Machine learning for cross-scale microscopy of viruses
por: Petkidis, Anthony, et al.
Publicado: (2023)

High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections
por: Olszewski, Dominik, et al.
Publicado: (2022)

Adenovirus entry: Stability, uncoating, and nuclear import
por: Greber, Urs F., et al.
Publicado: (2022)

The UPR sensor IRE1α and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections
por: Prasad, Vibhu, et al.
Publicado: (2020)

Infectio: a Generic Framework for Computational Simulation of Virus Transmission between Cells
por: Yakimovich, Artur, et al.
Publicado: (2016)

The endoplasmic reticulum unfolded protein response – homeostasis, cell death and evolution in virus infections
por: Prasad, Vibhu, et al.
Publicado: (2021)

Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton
por: Wang, I-Hsuan, et al.
Publicado: (2018)

Identification of broad anti-coronavirus chemical agents for repurposing against SARS-CoV-2 and variants of concern
por: Murer, Luca, et al.
Publicado: (2022)

The adenovirus major core protein VII is dispensable for virion assembly but is essential for lytic infection
por: Ostapchuk, Philomena, et al.
Publicado: (2017)

A viral ubiquitination switch attenuates innate immunity and triggers nuclear import of virion DNA and infection
por: Bauer, Michael, et al.
Publicado: (2021)

Microtubule-dependent Plus- and Minus End–directed Motilities Are Competing Processes for Nuclear Targeting of Adenovirus
por: Suomalainen, Maarit, et al.
Publicado: (1999)

Use of high throughput T cell receptor (TCR) DNA sequencing to characterize T cell infusion products and track clonal expansion in vivo
por: Strohl, Madeleine, et al.
Publicado: (2014)

Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality
por: Laskey, Sarah B., et al.
Publicado: (2016)

Select sequencing of clonally expanded CD8(+) T cells reveals limits to clonal expansion
por: Huang, Huang, et al.
Publicado: (2019)

Clonal expansion of human T lymphocytes initiated by dendritic cells
Publicado: (1989)

Clonal expansion of renal cell carcinoma-infiltrating T lymphocytes
por: Sittig, Simone P, et al.
Publicado: (2013)

Intrathecal T‐cell clonal expansions in patients with multiple sclerosis
por: de Paula Alves Sousa, Alessandra, et al.
Publicado: (2016)

RNF20 affects porcine adipocyte differentiation via regulation of mitotic clonal expansion
por: Zhao, Ying, et al.
Publicado: (2021)

Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids
por: Volle, Romain, et al.
Publicado: (2022)

Utilities for High-Throughput Analysis of B-Cell Clonal Lineages
por: Lees, William D., et al.
Publicado: (2015)

Clonal expansion of abnormal B cells in old NZB mice
Publicado: (1987)

Isolation of CD133+ Liver Stem Cells for Clonal Expansion
por: Rountree, C. Bart, et al.
Publicado: (2011)

The analysis of clonal expansions in normal and autoimmune B cell repertoires
por: Hershberg, Uri, et al.
Publicado: (2015)

Endothelial cell clonal expansion in the development of cerebral cavernous malformations
por: Malinverno, Matteo, et al.
Publicado: (2019)

T cell receptor repertoire in polymyositis: clonal expansion of autoaggressive CD8+ T cells
Publicado: (1995)

Multidisciplinary insight into clonal expansion of HTLV-1–infected cells in adult T-cell leukemia via modeling by deterministic finite automata coupled with high-throughput sequencing
por: Farmanbar, Amir, et al.
Publicado: (2017)

Synovial B Cells in Rheumatoid Arthritis: Clonal Expansion, Diversification, and Persistence
por: Chiorazzi, Nicholas, et al.
Publicado: (2000)

Clonal Expansion of Infected CD4+ T Cells in People Living with HIV
por: Coffin, John M., et al.
Publicado: (2021)

Clonal expansion and epigenetic inheritance of long-lasting NK cell memory
por: Rückert, Timo, et al.
Publicado: (2022)

An update on clonality: what smooth muscle cell type makes up the atherosclerotic plaque?
por: Schwartz, Stephen M., et al.
Publicado: (2018)

Inhibition of Poxvirus Gene Expression and Genome Replication by Bisbenzimide Derivatives
por: Yakimovich, Artur, et al.
Publicado: (2017)

Somatic mutation and clonal expansions in human tissues
por: Martincorena, Inigo
Publicado: (2019)

Dynamics of latent HIV under clonal expansion
por: Murray, John M.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9ldngl90355fa1br6glkhont8d