Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes

BACKGROUND: Drug metabolizing enzymes (DMEs) exhibit dramatic inter- and intra-individual variability in expression and activity. However, the mechanisms determining this variability have not been fully elucidated. The aim of this study was to evaluate the biological significance of DNA methylation...

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Detalles Bibliográficos
Autores principales: Habano, Wataru, Kawamura, Kohei, Iizuka, Natsuki, Terashima, Jun, Sugai, Tamotsu, Ozawa, Shogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587720/
https://www.ncbi.nlm.nih.gov/pubmed/26421064
http://dx.doi.org/10.1186/s13148-015-0136-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587720/
https://www.ncbi.nlm.nih.gov/pubmed/26421064
http://dx.doi.org/10.1186/s13148-015-0136-7

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