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The effects of arginase inhibitor on lung oxidative stress and inflammation caused by pneumoperitoneum in rats
BACKGROUND: Pneumoperitoneum-induced oxidative stress and organ injury are known to be associated with nitric oxide (NO) inactivation. Because arginase competes with NO synthase (NOS) for a common substrate, L-arginine, arginase inhibition may increase NO bioavailability. Therefore, we evaluated the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587728/ https://www.ncbi.nlm.nih.gov/pubmed/26415531 http://dx.doi.org/10.1186/s12871-015-0112-y |