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The effects of arginase inhibitor on lung oxidative stress and inflammation caused by pneumoperitoneum in rats

BACKGROUND: Pneumoperitoneum-induced oxidative stress and organ injury are known to be associated with nitric oxide (NO) inactivation. Because arginase competes with NO synthase (NOS) for a common substrate, L-arginine, arginase inhibition may increase NO bioavailability. Therefore, we evaluated the...

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Detalles Bibliográficos
Autores principales: Cho, Jin Sun, Oh, Young Jun, Kim, Ok Soo, Na, Sungwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587728/
https://www.ncbi.nlm.nih.gov/pubmed/26415531
http://dx.doi.org/10.1186/s12871-015-0112-y