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Changes in the Sterol Composition of the Plasma Membrane Affect Membrane Potential, Salt Tolerance and the Activity of Multidrug Resistance Pumps in Saccharomyces cerevisiae

We investigated the impact of the deletions of genes from the final steps in the biosynthesis of ergosterol (ERG6, ERG2, ERG3, ERG5, ERG4) on the physiological function of the Saccharomyces cerevisiae plasma membrane by a combination of biological tests and the diS-C(3)(3) fluorescence assay. Most o...

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Detalles Bibliográficos
Autores principales: Kodedová, Marie, Sychrová, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587746/
https://www.ncbi.nlm.nih.gov/pubmed/26418026
http://dx.doi.org/10.1371/journal.pone.0139306