TGFβ Pathway Inhibition Redifferentiates Human Pancreatic Islet β Cells Expanded In Vitro

In-vitro expansion of insulin-producing cells from adult human pancreatic islets could provide an abundant cell source for diabetes therapy. However, proliferation of β-cell-derived (BCD) cells is associated with loss of phenotype and epithelial-mesenchymal transition (EMT). Nevertheless, BCD cells...

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Detalles Bibliográficos
Autores principales: Toren-Haritan, Ginat, Efrat, Shimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587799/
https://www.ncbi.nlm.nih.gov/pubmed/26418361
http://dx.doi.org/10.1371/journal.pone.0139168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587799/
https://www.ncbi.nlm.nih.gov/pubmed/26418361
http://dx.doi.org/10.1371/journal.pone.0139168

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