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Differential replicative ability of clinical dengue virus isolates in an immunocompetent C57BL/6 mouse model
BACKGROUND: Several experimental animal models have been used to study the pathogenesis of dengue disease; however, most of the studies used laboratory-adapted viruses, which lack the virulence of viruses circulating in humans. The aim of this study was to analyze the ability of clinical Dengue viru...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587874/ https://www.ncbi.nlm.nih.gov/pubmed/26415508 http://dx.doi.org/10.1186/s12866-015-0520-7 |