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K(Ca)3.1-Dependent Hyperpolarization Enhances Intracellular Ca(2+) Signaling Induced by fMLF in Differentiated U937 Cells

Formylated peptides are chemotactic agents generated by pathogens. The most relevant peptide is fMLF (formyl-Met-Leu-Phe) which participates in several immune functions, such as chemotaxis, phagocytosis, cytokine release and generation of reactive oxygen species. In macrophages fMLF-dependent respon...

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Detalles Bibliográficos
Autores principales: Penna, Antonello, Stutzin, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587941/
https://www.ncbi.nlm.nih.gov/pubmed/26418693
http://dx.doi.org/10.1371/journal.pone.0139243