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Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles

Planar cell polarity (PCP) signaling controls the global orientation of surface structures, such as hairs and bristles, in both vertebrates and invertebrates. In Frizzled6 (-/-) (Fz6 (-/-)) mice, hair follicle orientations on the head and back are nearly random at birth, but reorient during early po...

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Detalles Bibliográficos
Autores principales: Chang, Hao, Cahill, Hugh, Smallwood, Philip M., Wang, Yanshu, Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587951/
https://www.ncbi.nlm.nih.gov/pubmed/26418459
http://dx.doi.org/10.1371/journal.pgen.1005532