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Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles
Planar cell polarity (PCP) signaling controls the global orientation of surface structures, such as hairs and bristles, in both vertebrates and invertebrates. In Frizzled6 (-/-) (Fz6 (-/-)) mice, hair follicle orientations on the head and back are nearly random at birth, but reorient during early po...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587951/ https://www.ncbi.nlm.nih.gov/pubmed/26418459 http://dx.doi.org/10.1371/journal.pgen.1005532 |