PKC-Dependent GlyT1 Ubiquitination Occurs Independent of Phosphorylation: Inespecificity in Lysine Selection for Ubiquitination

Neurotransmitter transporter ubiquitination is emerging as the main mechanism for endocytosis and sorting of cargo into lysosomes. In this study, we demonstrate PKC-dependent ubiquitination of three different isoforms of the glycine transporter 1 (GlyT1). Incubation of cells expressing transporter w...

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Detalles Bibliográficos
Autores principales: Barrera, Susana P., Castrejon-Tellez, Vicente, Trinidad, Margarita, Robles-Escajeda, Elisa, Vargas-Medrano, Javier, Varela-Ramirez, Armando, Miranda, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587969/
https://www.ncbi.nlm.nih.gov/pubmed/26418248
http://dx.doi.org/10.1371/journal.pone.0138897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587969/
https://www.ncbi.nlm.nih.gov/pubmed/26418248
http://dx.doi.org/10.1371/journal.pone.0138897

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