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Mitochondrial Impairment May Increase Cellular NAD(P)H: Resazurin Oxidoreductase Activity, Perturbing the NAD(P)H-Based Viability Assays

Cellular NAD(P)H-dependent oxidoreductase activity with artificial dyes (NAD(P)H-OR) is an indicator of viability, as the cellular redox state is important for biosynthesis and antioxidant defense. However, high NAD(P)H due to impaired mitochondrial oxidation, known as reductive stress, should incre...

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Detalles Bibliográficos
Autores principales:	Aleshin, Vasily A., Artiukhov, Artem V., Oppermann, Henry, Kazantsev, Alexey V., Lukashev, Nikolay V., Bunik, Victoria I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588044/ https://www.ncbi.nlm.nih.gov/pubmed/26308058 http://dx.doi.org/10.3390/cells4030427

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