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NAD(+)-Metabolizing Ectoenzymes in Remodeling Tumor–Host Interactions: The Human Myeloma Model

Nicotinamide adenine dinucleotide (NAD(+)) is an essential co-enzyme reported to operate both intra- and extracellularly. In the extracellular space, NAD(+) can elicit signals by binding purinergic P2 receptors or it can serve as the substrate for a chain of ectoenzymes. As a substrate, it is conver...

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Detalles Bibliográficos
Autores principales: Horenstein, Alberto L., Chillemi, Antonella, Quarona, Valeria, Zito, Andrea, Roato, Ilaria, Morandi, Fabio, Marimpietri, Danilo, Bolzoni, Marina, Toscani, Denise, Oldham, Robert J., Cuccioloni, Massimiliano, Sasser, A. Kate, Pistoia, Vito, Giuliani, Nicola, Malavasi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588049/
https://www.ncbi.nlm.nih.gov/pubmed/26393653
http://dx.doi.org/10.3390/cells4030520