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NAD(+)-Metabolizing Ectoenzymes in Remodeling Tumor–Host Interactions: The Human Myeloma Model
Nicotinamide adenine dinucleotide (NAD(+)) is an essential co-enzyme reported to operate both intra- and extracellularly. In the extracellular space, NAD(+) can elicit signals by binding purinergic P2 receptors or it can serve as the substrate for a chain of ectoenzymes. As a substrate, it is conver...
Autores principales: | Horenstein, Alberto L., Chillemi, Antonella, Quarona, Valeria, Zito, Andrea, Roato, Ilaria, Morandi, Fabio, Marimpietri, Danilo, Bolzoni, Marina, Toscani, Denise, Oldham, Robert J., Cuccioloni, Massimiliano, Sasser, A. Kate, Pistoia, Vito, Giuliani, Nicola, Malavasi, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588049/ https://www.ncbi.nlm.nih.gov/pubmed/26393653 http://dx.doi.org/10.3390/cells4030520 |
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