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Structural Basis of Targeting the Exportin CRM1 in Cancer

Recent studies have demonstrated the interference of nucleocytoplasmic trafficking with the establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly regulated and coordinated, involving different nuclear transport factors or receptors, importins and exportins, that med...

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Detalles Bibliográficos
Autores principales: Dickmanns, Achim, Monecke, Thomas, Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588050/
https://www.ncbi.nlm.nih.gov/pubmed/26402707
http://dx.doi.org/10.3390/cells4030538