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Bench to Bedside: Stability Studies of GMP Produced Trastuzumab-TCMC in Support of a Clinical Trial

The first-in-human phase 1 clinical radioimmunotherapy (RIT) trial with (212)Pb-1,4,7,10-tetraaza-1,4,7,10-tetra-(2-carbamoylmethyl)-cyclododecane-trastuzumab ((212)Pb-TCMC-trastuzumab) was completed in October 2014 as a joint effort at the University of Alabama (UAB) and the University of Californi...

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Detalles Bibliográficos
Autores principales: Milenic, Diane E., Baidoo, Kwamena E., Brechbiel, Martin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588176/
https://www.ncbi.nlm.nih.gov/pubmed/26230702
http://dx.doi.org/10.3390/ph8030435