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Anti-Apoptotic Gene Delivery with cyclo-(d-Trp-Tyr) Peptide Nanotube via Eye Drop Following Corneal Epithelial Debridement

Corneal keratocyte apoptosis triggered by cornel debridement is one mechanism of corneal disorders. In this study, the feasibility of cyclo-(d-Trp-Tyr) peptide nanotubes (PNTs) as carriers of caspase 3 silence shRNA delivery was assessed. A model of epithelial injury by epithelial debridement was ap...

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Detalles Bibliográficos
Autores principales: Lee, Yu-Hsing, Chang, Shwu-Fen, Liaw, Jiahorng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588189/
https://www.ncbi.nlm.nih.gov/pubmed/26193308
http://dx.doi.org/10.3390/pharmaceutics7030122