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Highly Effective Non-Viral Antitumor Gene Therapy System Comprised of Biocompatible Small Plasmid Complex Particles Consisting of pDNA, Anionic Polysaccharide, and Fully Deprotected Linear Polyethylenimine

We have reported that ternary complexes of plasmid DNA with conventional linear polyethylenimine (l-PEI) and certain polyanions were very stably dispersed, and, with no cryoprotectant, they could be freeze-dried and re-hydrated without the loss of transfection ability. These properties enabled the p...

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Detalles Bibliográficos
Autores principales: Koyama, Yoshiyuki, Sugiura, Kikuya, Yoshihara, Chieko, Inaba, Toshio, Ito, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588191/
https://www.ncbi.nlm.nih.gov/pubmed/26213961
http://dx.doi.org/10.3390/pharmaceutics7030152