Novel Antitumor Strategy Utilizing a Plasmid Expressing a Mycobacterium tuberculosis Antigen as a “Danger Signal” to Block Immune Escape of Tumor Cells

Immune escape of tumor cells is one of the main obstacles hindering the effectiveness of cancer immunotherapy. We developed a novel strategy to block immune escape by transfecting tumor cells in vivo with genes of pathogenic antigens from Mycobacterium tuberculosis (TB). This induces presentation of...

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Detalles Bibliográficos
Autores principales: Koyama, Yoshiyuki, Yoshihara, Chieko, Ito, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588192/
https://www.ncbi.nlm.nih.gov/pubmed/26213962
http://dx.doi.org/10.3390/pharmaceutics7030165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588192/
https://www.ncbi.nlm.nih.gov/pubmed/26213962
http://dx.doi.org/10.3390/pharmaceutics7030165

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