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Practical approaches for evaluating adrenal toxicity in nonclinical safety assessment

The adrenal gland has characteristic morphological and biochemical features that render it particularly susceptible to the actions of xenobiotics. As is the case with other endocrine organs, the adrenal gland is under the control of upstream organs (hypothalamic-pituitary system) in vivo, often maki...

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Detalles Bibliográficos
Autores principales: Inomata, Akira, Sasano, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588206/
https://www.ncbi.nlm.nih.gov/pubmed/26441474
http://dx.doi.org/10.1293/tox.2015-0025