Cargando…
Practical approaches for evaluating adrenal toxicity in nonclinical safety assessment
The adrenal gland has characteristic morphological and biochemical features that render it particularly susceptible to the actions of xenobiotics. As is the case with other endocrine organs, the adrenal gland is under the control of upstream organs (hypothalamic-pituitary system) in vivo, often maki...
Autores principales: | Inomata, Akira, Sasano, Hironobu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588206/ https://www.ncbi.nlm.nih.gov/pubmed/26441474 http://dx.doi.org/10.1293/tox.2015-0025 |
Ejemplares similares
-
Luteal toxicity evaluation in rats
por: Taketa, Yoshikazu
Publicado: (2021) -
Regulatory Consideration for the Nonclinical Safety Assessment of Gene Therapies
por: Moffit, Jeffrey S., et al.
Publicado: (2022) -
Considerations for the Nonclinical Safety Evaluation of Antibody–Drug Conjugates
por: Fisher, J. Edward
Publicado: (2021) -
Strategies for the Nonclinical Safety Assessment of Vaccines
por: Wolf, Jayanthi J., et al.
Publicado: (2012) -
Therapeutic antibodies: their mechanisms of action and the pathological
findings they induce in toxicity studies
por: Suzuki, Masami, et al.
Publicado: (2015)