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Disease-modifying effects of phosphocitrate and phosphocitrate-β-ethyl ester on partial meniscectomy-induced osteoarthritis

BACKGROUND: It is believed that phosphocitrate (PC) exerts its disease-modifying effects on osteoarthritis (OA) by inhibiting the formation of crystals. However, recent findings suggest that PC exerts its disease-modifying effect, at least in part, through a crystal-independent action. This study so...

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Detalles Bibliográficos
Autores principales: Sun, Yubo, Haines, Nikkole, Roberts, Andrea, Ruffolo, Michael, Mauerhan, David R., Mihalko, Kim L., Ingram, Jane, Cox, Michael, Hanley, Edward N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588234/
https://www.ncbi.nlm.nih.gov/pubmed/26424660
http://dx.doi.org/10.1186/s12891-015-0724-x