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Successful Treatment of Intracranial Glioblastoma Xenografts With a Monoamine Oxidase B-Activated Pro-Drug

The last major advance in the treatment of glioblastoma multiforme (GBM) was the introduction of temozolomide in 1999. Treatment with temozolomide following surgical debulking extends survival rate compared to radiotherapy and debulking alone. However, virtually all glioblastoma patients experience...

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Detalles Bibliográficos
Autores principales: Sharpe, Martyn A., Livingston, Andrew D., Gist, Taylor L., Ghosh, Pardip, Han, Junyan, Baskin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588367/
https://www.ncbi.nlm.nih.gov/pubmed/26501110
http://dx.doi.org/10.1016/j.ebiom.2015.08.013