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Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

BACKGROUND: Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundamental to improving the way we treat this disease. As yet, there are no validated descriptions of prostate cancer subgroups derived from integrated genomics linked with clinical outcome. METHODS: In a stu...

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Detalles Bibliográficos
Autores principales: Ross-Adams, H., Lamb, A.D., Dunning, M.J., Halim, S., Lindberg, J., Massie, C.M., Egevad, L.A., Russell, R., Ramos-Montoya, A., Vowler, S.L., Sharma, N.L., Kay, J., Whitaker, H., Clark, J., Hurst, R., Gnanapragasam, V.J., Shah, N.C., Warren, A.Y., Cooper, C.S., Lynch, A.G., Stark, R., Mills, I.G., Grönberg, H., Neal, D.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588396/
https://www.ncbi.nlm.nih.gov/pubmed/26501111
http://dx.doi.org/10.1016/j.ebiom.2015.07.017