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Meclizine Preconditioning Protects the Kidney Against Ischemia–Reperfusion Injury

Global or local ischemia contributes to the pathogenesis of acute kidney injury (AKI). Currently there are no specific therapies to prevent AKI. Potentiation of glycolytic metabolism and attenuation of mitochondrial respiration may decrease cell injury and reduce reactive oxygen species generation f...

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Detalles Bibliográficos
Autores principales: Kishi, Seiji, Campanholle, Gabriela, Gohil, Vishal M., Perocchi, Fabiana, Brooks, Craig R., Morizane, Ryuji, Sabbisetti, Venkata, Ichimura, Takaharu, Mootha, Vamsi K., Bonventre, Joseph V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588407/
https://www.ncbi.nlm.nih.gov/pubmed/26501107
http://dx.doi.org/10.1016/j.ebiom.2015.07.035