AAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats

AAV9 has emerged as an efficient adeno-associated virus (AAV) serotype for gene transfer to the central nervous system. We have used this technique to study aspects of amyotrophic lateral sclerosis (ALS) by administering AAV encoding the ALS-related gene transactive response DNA binding protein of 4...

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Detalles Bibliográficos
Autores principales: Jackson, Kasey L, Dayton, Robert D, Klein, Ronald L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588447/
https://www.ncbi.nlm.nih.gov/pubmed/26445725
http://dx.doi.org/10.1038/mtm.2015.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588447/
https://www.ncbi.nlm.nih.gov/pubmed/26445725
http://dx.doi.org/10.1038/mtm.2015.36

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