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AAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats
AAV9 has emerged as an efficient adeno-associated virus (AAV) serotype for gene transfer to the central nervous system. We have used this technique to study aspects of amyotrophic lateral sclerosis (ALS) by administering AAV encoding the ALS-related gene transactive response DNA binding protein of 4...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588447/ https://www.ncbi.nlm.nih.gov/pubmed/26445725 http://dx.doi.org/10.1038/mtm.2015.36 |