Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic Mice

Down syndrome (DS) mouse models exhibit cognitive deficits, and are used for studying the neuronal basis of DS pathology. To understand the differences in the physiology of DS model neurons, we used dissociated neuronal cultures from the hippocampi of Ts65Dn and Tc1 DS mice. Imaging of [Ca(2+)]i and...

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Detalles Bibliográficos
Autores principales: Stern, Shani, Segal, Menahem, Moses, Elisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588457/
https://www.ncbi.nlm.nih.gov/pubmed/26501103
http://dx.doi.org/10.1016/j.ebiom.2015.07.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588457/
https://www.ncbi.nlm.nih.gov/pubmed/26501103
http://dx.doi.org/10.1016/j.ebiom.2015.07.038

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