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TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice

OBJECTIVE: Tissue inhibitor of metalloproteinase 3 (TIMP3) is an extracellular matrix (ECM) bound protein, which has been shown to be downregulated in human subjects and experimental models with cardiometabolic disorders, including type 2 diabetes mellitus, hypertension and atherosclerosis. The aim...

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Detalles Bibliográficos
Autores principales: Stöhr, Robert, Kappel, Ben Arpad, Carnevale, Daniela, Cavalera, Michele, Mavilio, Maria, Arisi, Ivan, Fardella, Valentina, Cifelli, Giuseppe, Casagrande, Viviana, Rizza, Stefano, Cattaneo, Antonino, Mauriello, Alessandro, Menghini, Rossella, Lembo, Giuseppe, Federici, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588459/
https://www.ncbi.nlm.nih.gov/pubmed/26500845
http://dx.doi.org/10.1016/j.molmet.2015.07.007